{"symbol":"MT-ND1","synonyms":["MTND1","ND1"],"name":"NADH dehydrogenase, subunit 1 (complex I)","description":"Enables NADH dehydrogenase (ubiquinone) activity. Involved in mitochondrial electron transport, NADH to ubiquinone and mitochondrial respiratory chain complex I assembly. Located in mitochondrial membrane. Part of mitochondrial inner membrane and respiratory chain complex I. Implicated in several diseases, including MELAS syndrome; neurodegenerative disease (multiple); optic nerve disease (multiple); toxic shock syndrome; and type 2 diabetes mellitus. Biomarker of Alzheimer\u0027s disease; Parkinson\u0027s disease; and multiple sclerosis. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":4535,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4535","proteins":[{"symbol":"NU1M_HUMAN","href":"/api/1.0/protein/NU1M_HUMAN"}],"hgncRootFamilies":[{"name":"Mitochondrial respiratory chain complexes","href":"/api/1.0/gene_family/Mitochondrial+respiratory+chain+complexes"}]}