{"symbol":"MTCH2","synonyms":["MIMP","HSPC032","SLC25A50"],"name":"mitochondrial carrier 2","description":"This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target that can produce two isoforms from the same mRNA by use of alternative in-frame translation termination codons. [provided by RefSeq, Dec 2017]","ncbiEntrezGeneId":23788,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/23788","proteins":[{"symbol":"MTCH2_HUMAN","href":"/api/1.0/protein/MTCH2_HUMAN"}],"hgncRootFamilies":[{"name":"Solute carriers (SLC)","href":"/api/1.0/gene_family/Solute+carriers+%28SLC%29"}]}