{"symbol":"MTDH","synonyms":["3D3","AEG1","LYRIC/3D3","LYRIC","AEG-1"],"name":"metadherin","description":"Enables NF-kappaB binding activity; double-stranded RNA binding activity; and transcription coactivator activity. Involved in several processes, including lipopolysaccharide-mediated signaling pathway; positive regulation of intracellular signal transduction; and regulation of DNA-templated transcription. Located in endoplasmic reticulum; nuclear lumen; and perinuclear region of cytoplasm. Implicated in hepatocellular carcinoma. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":92140,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/92140","proteins":[{"symbol":"LYRIC_HUMAN","href":"/api/1.0/protein/LYRIC_HUMAN"}],"hgncRootFamilies":[]}