{"symbol":"MUC5B","synonyms":["MUC-5B","MG1"],"name":"mucin 5B, oligomeric mucus/gel-forming","description":"This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases. [provided by RefSeq, Jul 2010]","ncbiEntrezGeneId":727897,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/727897","proteins":[{"symbol":"MUC5B_HUMAN","href":"/api/1.0/protein/MUC5B_HUMAN"}],"hgncRootFamilies":[{"name":"Mucins (MUC)","href":"/api/1.0/gene_family/Mucins+%28MUC%29"}]}