{"symbol":"MYBPC3","synonyms":["CMD1MM","CMH4","MYBP-C","LVNC10"],"name":"myosin binding protein C, cardiac","description":"MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3 is expressed exclusively in heart muscle and is a key regulator of cardiac contraction. Mutations in this gene are a frequent cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, May 2022]","ncbiEntrezGeneId":4607,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4607","proteins":[{"symbol":"MYPC3_HUMAN","href":"/api/1.0/protein/MYPC3_HUMAN"}],"hgncRootFamilies":[{"name":"Fibronectin type III domain containing","href":"/api/1.0/gene_family/Fibronectin+type+III+domain+containing"},{"name":"Immunoglobulin superfamily domain containing","href":"/api/1.0/gene_family/Immunoglobulin+superfamily+domain+containing"}]}