{"symbol":"MYH2","synonyms":["MYH2A","MYHC-IIA","MYHSA2","MYHC-2A","MYPOP","IBM3","MYHAS8"],"name":"myosin, heavy chain 2, skeletal muscle, adult","description":"Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in inclusion body myopathy-3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2009]","ncbiEntrezGeneId":4620,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4620","proteins":[{"symbol":"MYH2_HUMAN","href":"/api/1.0/protein/MYH2_HUMAN"}],"hgncRootFamilies":[{"name":"Myosins (MYH, MYO)","href":"/api/1.0/gene_family/Myosins+%28MYH%2C+MYO%29"}]}