{"symbol":"MYH3","synonyms":["MYHSE1","DA8","HEMHC","DA2B","SMHCE","DA2A","MYHC-EMB"],"name":"myosin, heavy chain 3, skeletal muscle, embryonic","description":"Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. This gene is a member of the MYH family and encodes a protein with an IQ domain and a myosin head-like domain. Mutations in this gene have been associated with two congenital contracture (arthrogryposis) syndromes, Freeman-Sheldon syndrome and Sheldon-Hall syndrome. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":4621,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4621","proteins":[{"symbol":"MYH3_HUMAN","href":"/api/1.0/protein/MYH3_HUMAN"}],"hgncRootFamilies":[{"name":"Myosins (MYH, MYO)","href":"/api/1.0/gene_family/Myosins+%28MYH%2C+MYO%29"}]}