{"symbol":"MYO6","synonyms":["DFNA22","Myo6-007","DFNB37","Myo6-008"],"name":"myosin VI","description":"This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]","ncbiEntrezGeneId":4646,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4646","proteins":[{"symbol":"MYO6_HUMAN","href":"/api/1.0/protein/MYO6_HUMAN"}],"hgncRootFamilies":[{"name":"Myosins (MYH, MYO)","href":"/api/1.0/gene_family/Myosins+%28MYH%2C+MYO%29"}]}