{"symbol":"MYO7A","synonyms":["NSRD2","MYOVIIA","USH1B","DFNB2","DFNA11","MYU7A"],"name":"myosin VIIA","description":"This gene is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. This gene encodes an unconventional myosin with a very short tail. Defects in this gene are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":4647,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4647","proteins":[{"symbol":"MYO7A_HUMAN","href":"/api/1.0/protein/MYO7A_HUMAN"}],"hgncRootFamilies":[{"name":"Myosins (MYH, MYO)","href":"/api/1.0/gene_family/Myosins+%28MYH%2C+MYO%29"},{"name":"A-kinase anchor proteins (AKAP)","href":"/api/1.0/gene_family/A-kinase+anchor+proteins+%28AKAP%29"}]}