{"symbol":"MYOZ2","synonyms":["CMH16","C4ORF5","FATZ-2"],"name":"myozenin 2","description":"The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder. [provided by RefSeq, Aug 2011]","ncbiEntrezGeneId":51778,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/51778","proteins":[{"symbol":"MYOZ2_HUMAN","href":"/api/1.0/protein/MYOZ2_HUMAN"}],"hgncRootFamilies":[]}