{"symbol":"N4BP2","synonyms":["B3BP"],"name":"NEDD4 binding protein 2","description":"This gene encodes a protein containing a polynucleotide kinase domain (PNK) near the N-terminal region, and a Small MutS Related (Smr) domain near the C-terminal region. The encoded protein can bind to both B-cell leukemia/lymphoma 3 (BCL-3) and neural precursor cell expressed, developmentally downregulated 4, (Nedd4) proteins. This protein binds and hydrolyzes ATP, may function as a 5\u0027-polynucleotide kinase, and has the capacity to be a ubiquitylation substrate. This protein may play a role in transcription-coupled DNA repair or genetic recombination. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]","ncbiEntrezGeneId":55728,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/55728","proteins":[{"symbol":"N4BP2_HUMAN","href":"/api/1.0/protein/N4BP2_HUMAN"}],"hgncRootFamilies":[]}