{"symbol":"NACC1","synonyms":["NAC-1","NECFM","BEND8","BTBD14B","BTBD30"],"name":"nucleus accumbens associated 1, BEN and BTB (POZ) domain containing","description":"This gene encodes a member of the BTB/POZ protein family. BTB/POZ proteins are involved in several cellular processes including proliferation, apoptosis and transcription regulation. The encoded protein is a transcriptional repressor that plays a role in stem cell self-renewal and pluripotency maintenance. The encoded protein also suppresses transcription of the candidate tumor suppressor Gadd45GIP1, and expression of this gene may play a role in the progression of multiple types of cancer. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Feb 2012]","ncbiEntrezGeneId":112939,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/112939","proteins":[{"symbol":"NACC1_HUMAN","href":"/api/1.0/protein/NACC1_HUMAN"}],"hgncRootFamilies":[{"name":"BEN domain containing (BEND)","href":"/api/1.0/gene_family/BEN+domain+containing+%28BEND%29"},{"name":"BTB (POZ) domain containing (BTBD)","href":"/api/1.0/gene_family/BTB+%28POZ%29+domain+containing+%28BTBD%29"}]}