{"symbol":"NACC2","synonyms":["BTBD31","RBB","BTBD14","BEND9","BTBD14A","NAC-2"],"name":"NACC family member 2, BEN and BTB (POZ) domain containing","description":"Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; histone deacetylase binding activity; and protein homodimerization activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage; and protein homooligomerization. Located in chromatin; mitochondrion; and nucleolus. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":138151,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/138151","proteins":[{"symbol":"NACC2_HUMAN","href":"/api/1.0/protein/NACC2_HUMAN"}],"hgncRootFamilies":[{"name":"BEN domain containing (BEND)","href":"/api/1.0/gene_family/BEN+domain+containing+%28BEND%29"},{"name":"BTB (POZ) domain containing (BTBD)","href":"/api/1.0/gene_family/BTB+%28POZ%29+domain+containing+%28BTBD%29"}]}