{"symbol":"NAGLU","synonyms":["MPS3B","UFHSD","NAG","CMT2V","MPS-IIIB"],"name":"N-acetylglucosaminidase, alpha","description":"This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":4669,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4669","proteins":[{"symbol":"ANAG_HUMAN","href":"/api/1.0/protein/ANAG_HUMAN"}],"hgncRootFamilies":[]}