{"symbol":"NAT2","synonyms":["AAC2","PNAT","NAT-2"],"name":"N-acetyltransferase 2 (arylamine N-acetyltransferase)","description":"This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second polymorphic arylamine N-acetyltransferase gene (NAT1), is located near this gene (NAT2). [provided by RefSeq, Sep 2019]","ncbiEntrezGeneId":10,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10","proteins":[{"symbol":"ARY2_HUMAN","href":"/api/1.0/protein/ARY2_HUMAN"}],"hgncRootFamilies":[]}