{"symbol":"NCBP1","synonyms":["CBP80","NCBP","STO1"],"name":"nuclear cap binding protein subunit 1, 80kDa","description":"The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5\u0027 cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3\u0027-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":4686,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4686","proteins":[{"symbol":"NCBP1_HUMAN","href":"/api/1.0/protein/NCBP1_HUMAN"}],"hgncRootFamilies":[]}