{"symbol":"NEDD9","synonyms":["CASL","CASS2","HEF1","CAS2","CAS-L"],"name":"neural precursor cell expressed, developmentally down-regulated 9","description":"The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]","ncbiEntrezGeneId":4739,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4739","proteins":[{"symbol":"CASL_HUMAN","href":"/api/1.0/protein/CASL_HUMAN"}],"hgncRootFamilies":[{"name":"Cas scaffolding proteins (CASS)","href":"/api/1.0/gene_family/Cas+scaffolding+proteins+%28CASS%29"}]}