{"symbol":"NELFB","synonyms":["COBRA1","NELF-B"],"name":"negative elongation factor complex member B","description":"NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM, Mar 2008]","ncbiEntrezGeneId":25920,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/25920","proteins":[{"symbol":"NELFB_HUMAN","href":"/api/1.0/protein/NELFB_HUMAN"}],"hgncRootFamilies":[]}