{"symbol":"NELFE","synonyms":["D6S45","NELF-E","RDBP"],"name":"negative elongation factor complex member E","description":"The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":7936,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/7936","proteins":[{"symbol":"NELFE_HUMAN","href":"/api/1.0/protein/NELFE_HUMAN"}],"hgncRootFamilies":[{"name":"RNA binding motif containing (RBM)","href":"/api/1.0/gene_family/RNA+binding+motif+containing+%28RBM%29"}]}