{"symbol":"NEO1","synonyms":["NTN1R2","IGDCC2","NGN"],"name":"neogenin 1","description":"This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]","ncbiEntrezGeneId":4756,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4756","proteins":[{"symbol":"NEO1_HUMAN","href":"/api/1.0/protein/NEO1_HUMAN"}],"hgncRootFamilies":[{"name":"Fibronectin type III domain containing","href":"/api/1.0/gene_family/Fibronectin+type+III+domain+containing"},{"name":"Immunoglobulin superfamily domain containing","href":"/api/1.0/gene_family/Immunoglobulin+superfamily+domain+containing"}]}