{"symbol":"NFATC2","synonyms":["NFATP","NFAT1"],"name":"nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2","description":"This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012]","ncbiEntrezGeneId":4773,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4773","proteins":[{"symbol":"NFAC2_HUMAN","href":"/api/1.0/protein/NFAC2_HUMAN"}],"hgncRootFamilies":[{"name":"Nuclear factors of activated T-cells  (NFAT)","href":"/api/1.0/gene_family/Nuclear+factors+of+activated+T-cells++%28NFAT%29"}]}