{"symbol":"NFATC4","synonyms":["NF-AT3","NF-ATC4","NFAT3"],"name":"nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4","description":"This gene encodes a member of the nuclear factor of activated T cells (NFAT) protein family. The encoded protein is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase, calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of interleukin-2 and interleukin-4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]","ncbiEntrezGeneId":4776,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4776","proteins":[{"symbol":"NFAC4_HUMAN","href":"/api/1.0/protein/NFAC4_HUMAN"}],"hgncRootFamilies":[{"name":"Nuclear factors of activated T-cells  (NFAT)","href":"/api/1.0/gene_family/Nuclear+factors+of+activated+T-cells++%28NFAT%29"}]}