{"symbol":"NFU1","synonyms":["NIFUC","HIRIP","HIRIP5","NFU","MMDS1","CGI-33"],"name":"NFU1 iron-sulfur cluster scaffold","description":"This gene encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. The encoded protein assembles and transfers 4Fe-4S clusters to target apoproteins including succinate dehydrogenase and lipoic acid synthase. Mutations in this gene are a cause of multiple mitochondrial dysfunctions syndrome-1, and pseudogenes of this gene are located on the short arms of chromosomes 1 and 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]","ncbiEntrezGeneId":27247,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/27247","proteins":[{"symbol":"NFU1_HUMAN","href":"/api/1.0/protein/NFU1_HUMAN"}],"hgncRootFamilies":[]}