{"symbol":"NLRC4","synonyms":["AIFEC","CLANC","CLANA","IPAF","CLR2.1","CARD12","CLAND","FCAS4","CLAN","CLAN1","CLANB"],"name":"NLR family, CARD domain containing 4","description":"This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]","ncbiEntrezGeneId":58484,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/58484","proteins":[{"symbol":"NLRC4_HUMAN","href":"/api/1.0/protein/NLRC4_HUMAN"}],"hgncRootFamilies":[{"name":"NLR family (NLR)","href":"/api/1.0/gene_family/NLR+family+%28NLR%29"}]}