{"symbol":"NLRP13","synonyms":["CLR19.7","NOD14","PAN13","NALP13"],"name":"NLR family, pyrin domain containing 13","description":"This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]","ncbiEntrezGeneId":126204,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/126204","proteins":[{"symbol":"NAL13_HUMAN","href":"/api/1.0/protein/NAL13_HUMAN"}],"hgncRootFamilies":[{"name":"NLR family (NLR)","href":"/api/1.0/gene_family/NLR+family+%28NLR%29"}]}