{"symbol":"NLRP14","synonyms":["CLR11.2","GC-LRR","PAN8","NALP14"],"name":"NLR family, pyrin domain containing 14","description":"The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":338323,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/338323","proteins":[{"symbol":"NAL14_HUMAN","href":"/api/1.0/protein/NAL14_HUMAN"}],"hgncRootFamilies":[{"name":"NLR family (NLR)","href":"/api/1.0/gene_family/NLR+family+%28NLR%29"}]}