{"symbol":"NMBR","synonyms":["BB1","NMB-R","BB1R"],"name":"neuromedin B receptor","description":"This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]","ncbiEntrezGeneId":4829,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4829","proteins":[{"symbol":"NMBR_HUMAN","href":"/api/1.0/protein/NMBR_HUMAN"}],"hgncRootFamilies":[{"name":"Bombesin receptors","href":"/api/1.0/gene_family/Bombesin+receptors"}]}