{"symbol":"NMT1","synonyms":["NMT"],"name":"N-myristoyltransferase 1","description":"Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1; MIM 139311) (Duronio et al., 1992 [PubMed 1570339]).[supplied by OMIM, Nov 2008]","ncbiEntrezGeneId":4836,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4836","proteins":[{"symbol":"NMT1_HUMAN","href":"/api/1.0/protein/NMT1_HUMAN"}],"hgncRootFamilies":[]}