{"symbol":"NOS3","synonyms":["ENOS","ECNOS"],"name":"nitric oxide synthase 3 (endothelial cell)","description":"Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016]","ncbiEntrezGeneId":4846,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4846","proteins":[{"symbol":"NOS3_HUMAN","href":"/api/1.0/protein/NOS3_HUMAN"}],"hgncRootFamilies":[]}