{"symbol":"NPL","synonyms":["C112","C1ORF13","NAL","NPL1"],"name":"N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)","description":"This gene encodes a member of the N-acetylneuraminate lyase sub-family of (beta/alpha)(8)-barrel enzymes. N-acetylneuraminate lyases regulate cellular concentrations of N-acetyl-neuraminic acid (sialic acid) by mediating the reversible conversion of sialic acid into N-acetylmannosamine and pyruvate. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]","ncbiEntrezGeneId":80896,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/80896","proteins":[{"symbol":"NPL_HUMAN","href":"/api/1.0/protein/NPL_HUMAN"}],"hgncRootFamilies":[]}