{"symbol":"NPY1R","synonyms":["NPYR","NPY1-R"],"name":"neuropeptide Y receptor Y1","description":"This gene belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity. [provided by RefSeq, Aug 2013]","ncbiEntrezGeneId":4886,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4886","proteins":[{"symbol":"NPY1R_HUMAN","href":"/api/1.0/protein/NPY1R_HUMAN"}],"hgncRootFamilies":[{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"}]}