{"symbol":"NR2C1","synonyms":["TR2"],"name":"nuclear receptor subfamily 2, group C, member 1","description":"This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":7181,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/7181","proteins":[{"symbol":"NR2C1_HUMAN","href":"/api/1.0/protein/NR2C1_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}