{"symbol":"NRTN","synonyms":["NTN"],"name":"neurturin","description":"This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease. [provided by RefSeq, Aug 2016]","ncbiEntrezGeneId":4902,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4902","proteins":[{"symbol":"NRTN_HUMAN","href":"/api/1.0/protein/NRTN_HUMAN"}],"hgncRootFamilies":[{"name":"Endogenous ligands","href":"/api/1.0/gene_family/Endogenous+ligands"}]}