{"symbol":"NSUN2","synonyms":["MISU","SAKI","MRT5","TRM4"],"name":"NOP2/Sun RNA methyltransferase family, member 2","description":"This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2011]","ncbiEntrezGeneId":54888,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/54888","proteins":[{"symbol":"NSUN2_HUMAN","href":"/api/1.0/protein/NSUN2_HUMAN"}],"hgncRootFamilies":[{"name":"NOP2/Sun domain containing (NSUN)","href":"/api/1.0/gene_family/NOP2%24slash%24Sun+domain+containing+%28NSUN%29"}]}