{"symbol":"NUF2","synonyms":["CT106","CDCA1","NUF2R"],"name":"NUF2, NDC80 kinetochore complex component","description":"This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":83540,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/83540","proteins":[{"symbol":"NUF2_HUMAN","href":"/api/1.0/protein/NUF2_HUMAN"}],"hgncRootFamilies":[]}