{"symbol":"NUMB","synonyms":["C14ORF41","S171","C14_5527"],"name":"numb homolog (Drosophila)","description":"The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]","ncbiEntrezGeneId":8650,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8650","proteins":[{"symbol":"NUMB_HUMAN","href":"/api/1.0/protein/NUMB_HUMAN"}],"hgncRootFamilies":[]}