{"symbol":"ODC1","synonyms":["ODC"],"name":"ornithine decarboxylase 1","description":"This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2013]","ncbiEntrezGeneId":4953,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4953","proteins":[{"symbol":"DCOR_HUMAN","href":"/api/1.0/protein/DCOR_HUMAN"}],"hgncRootFamilies":[]}