{"symbol":"OLR1","synonyms":["LOXIN","CLEC8A","LOX1","SCARE1","SLOX1"],"name":"oxidized low density lipoprotein (lectin-like) receptor 1","description":"This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer\u0027s disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]","ncbiEntrezGeneId":4973,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4973","proteins":[{"symbol":"OLR1_HUMAN","href":"/api/1.0/protein/OLR1_HUMAN"}],"hgncRootFamilies":[{"name":"C-type lectin domain family (CLEC)","href":"/api/1.0/gene_family/C-type+lectin+domain+family+%28CLEC%29"}]}