{"symbol":"OS9","synonyms":["ERLEC2","OS-9"],"name":"osteosarcoma amplified 9, endoplasmic reticulum lectin","description":"This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":10956,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10956","proteins":[{"symbol":"OS9_HUMAN","href":"/api/1.0/protein/OS9_HUMAN"}],"hgncRootFamilies":[]}