{"symbol":"OSBPL2","synonyms":["ORP2","DNFA67","DFNA67","ORP-2"],"name":"oxysterol binding protein-like 2","description":"This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2014]","ncbiEntrezGeneId":9885,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9885","proteins":[{"symbol":"OSBL2_HUMAN","href":"/api/1.0/protein/OSBL2_HUMAN"}],"hgncRootFamilies":[{"name":"Oxysterol binding proteins (OSBP)","href":"/api/1.0/gene_family/Oxysterol+binding+proteins+%28OSBP%29"}]}