{"symbol":"OSBPL8","synonyms":["OSBP10","MST120","MSTP120","ORP8"],"name":"oxysterol binding protein-like 8","description":"This gene encodes a member of a family of proteins containing an N-terminal pleckstrin homology domain and a highly conserved C-terminal oxysterol-binding protein-like sterol-binding domain. It binds mutliple lipid-containing molecules, including phosphatidylserine, phosphatidylinositol 4-phosphate (PI4P) and oxysterol, and promotes their exchange between the endoplasmic reticulum and the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]","ncbiEntrezGeneId":114882,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/114882","proteins":[{"symbol":"OSBL8_HUMAN","href":"/api/1.0/protein/OSBL8_HUMAN"}],"hgncRootFamilies":[{"name":"Pleckstrin homology domain containing (PLEKH)","href":"/api/1.0/gene_family/Pleckstrin+homology+domain+containing+%28PLEKH%29"},{"name":"Oxysterol binding proteins (OSBP)","href":"/api/1.0/gene_family/Oxysterol+binding+proteins+%28OSBP%29"}]}