{"symbol":"OSCAR","synonyms":["PIGR3","PIGR-3"],"name":"osteoclast associated, immunoglobulin-like receptor","description":"Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]","ncbiEntrezGeneId":126014,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/126014","proteins":[{"symbol":"OSCAR_HUMAN","href":"/api/1.0/protein/OSCAR_HUMAN"}],"hgncRootFamilies":[{"name":"Immunoglobulin superfamily domain containing","href":"/api/1.0/gene_family/Immunoglobulin+superfamily+domain+containing"}]}