{"symbol":"P2RY1","synonyms":["SARCC","P2Y1"],"name":"purinergic receptor P2Y, G-protein coupled, 1","description":"The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":5028,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5028","proteins":[{"symbol":"P2RY1_HUMAN","href":"/api/1.0/protein/P2RY1_HUMAN"}],"hgncRootFamilies":[{"name":"Purinergic receptors (P2R)","href":"/api/1.0/gene_family/Purinergic+receptors+%28P2R%29"},{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"}]}