{"symbol":"PABPC1","synonyms":["PAB1","PABPC2","PABPL1","PABP"],"name":"poly(A) binding protein, cytoplasmic 1","description":"This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3\u0027 poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug 2010]","ncbiEntrezGeneId":26986,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/26986","proteins":[{"symbol":"PABP1_HUMAN","href":"/api/1.0/protein/PABP1_HUMAN"}],"hgncRootFamilies":[{"name":"RNA binding motif containing (RBM)","href":"/api/1.0/gene_family/RNA+binding+motif+containing+%28RBM%29"}]}