{"symbol":"PADI6","synonyms":["HPADVI","PREMBL2"],"name":"peptidyl arginine deiminase, type VI","description":"This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. This protein may play a role in cytoskeletal reorganization in the egg and in early embryo development. [provided by RefSeq, Sep 2012]","ncbiEntrezGeneId":353238,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/353238","proteins":[{"symbol":"PADI6_HUMAN","href":"/api/1.0/protein/PADI6_HUMAN"}],"hgncRootFamilies":[{"name":"Peptidyl arginine deiminases (PADI)","href":"/api/1.0/gene_family/Peptidyl+arginine+deiminases+%28PADI%29"}]}