{"symbol":"PAGR1","synonyms":["C16ORF53","PA1"],"name":"PAXIP1 associated glutamate-rich protein 1","description":"Enables nuclear estrogen receptor binding activity. Involved in positive regulation of cell cycle G1/S phase transition; positive regulation of intracellular estrogen receptor signaling pathway; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of MLL3/4 complex. Biomarker of esophagus squamous cell carcinoma. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":79447,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/79447","proteins":[{"symbol":"PAGR1_HUMAN","href":"/api/1.0/protein/PAGR1_HUMAN"}],"hgncRootFamilies":[]}