{"symbol":"PARP3","synonyms":["ARTD3","PADPRT-3","ADPRT3"],"name":"poly (ADP-ribose) polymerase family, member 3","description":"The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":10039,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10039","proteins":[{"symbol":"PARP3_HUMAN","href":"/api/1.0/protein/PARP3_HUMAN"}],"hgncRootFamilies":[{"name":"Poly (ADP-ribose) polymerases (PARP)","href":"/api/1.0/gene_family/Poly+%28ADP-ribose%29+polymerases+%28PARP%29"}]}