{"symbol":"PAX7","synonyms":["RMS2","HUP1","PAX7B"],"name":"paired box 7","description":"This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]","ncbiEntrezGeneId":5081,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5081","proteins":[{"symbol":"PAX7_HUMAN","href":"/api/1.0/protein/PAX7_HUMAN"}],"hgncRootFamilies":[{"name":"Homeoboxes","href":"/api/1.0/gene_family/Homeoboxes"},{"name":"Paired boxes (PAX)","href":"/api/1.0/gene_family/Paired+boxes+%28PAX%29"}]}