{"symbol":"PBRM1","synonyms":["BAF180","PB1"],"name":"polybromo 1","description":"This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma. [provided by RefSeq, Feb 2012]","ncbiEntrezGeneId":55193,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/55193","proteins":[{"symbol":"PB1_HUMAN","href":"/api/1.0/protein/PB1_HUMAN"}],"hgncRootFamilies":[]}