{"symbol":"PBX2","synonyms":["PBX2MHC","HOX12","G17"],"name":"pre-B-cell leukemia homeobox 2","description":"This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":5089,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5089","proteins":[{"symbol":"PBX2_HUMAN","href":"/api/1.0/protein/PBX2_HUMAN"}],"hgncRootFamilies":[{"name":"Homeoboxes","href":"/api/1.0/gene_family/Homeoboxes"}]}